Fig. 1.

Comparison of nicotine delivery systems. Schematic representation of commercially available vaping devices and their different components. The delivery systems of nicotine in vaping devices are very different from traditional cigarettes that generate smoke by combustion of tobacco and are inhaled through a filter [1]. Tank e-cigarettes are battery-powered devices that deliver a charge to the metal coil when the activation “on/off button” is pressed, which heats the e-liquid in the cartridge, generating vapor that is inhaled through the mouthpiece [1], [2]. On the other hand, single-use e-cigarettes do not utilize a mechanical ‘on’ trigger but activate vapor production through the user’s suction on a disposable, combined cartridge, and mouthpiece [2], [6].