Table 2. Diagnostic criteria of IgG4-related hypophysitis

Note: Diagnosis may be based on Criterion 1 or a combination of Criteria 2 and 3 or Criteria 2, 4 and 5.

Criterion 1	Histological confirmation.Lymphoplasmacytic infiltration of damaged tissue of pituitary gland with over 10 IgG4-positive plasma cells
Criterion 2	MRI confirmation.Pituitary gland and/or pituitary stalk swelling
Criterion 3	Histologically confirmed IgG4-associated disease in another organ
Criterion 4	Blood serum test confirmation.Elevated IgG4 in blood serum (over 140 mg/dl)
Criterion 5	Therapeutic response to glucocorticosteroids.Pituitary gland volume decrease and clinical improvement as a result of glucocorticosteroids treatment