Table 2:
Estimated effects (β coefficient† (95% Confidence interval)) of MedDiet on the rate of change in global cognitive scores among Chicago Health and Aging Project participants, Interaction model and stratified by Low and High Western diet score over the average follow-up of 6.3 (± 2.8)years †‡§¶
| N | Tertile 1 | Tertile 2 β (95% CI) | Tertile 3 β (95% CI) | P for trend | |
|---|---|---|---|---|---|
| MedDiet association, overall | |||||
|
| |||||
| Basic model | 5001 | Ref | 0.004 (−0.004, 0.012) | 0.015 (0.007, 0.024) | 0.0005 |
|
| |||||
| Basic + CVD§ | 4959 | Ref | 0.003 (−0.004, 0.011) | 0.015 (0.006, 0.023) | 0.0006 |
|
| |||||
| Interaction model ‡ betas for the MedDiet*time and MedDiet*Western diet*time interaction term | |||||
|
| |||||
| MedDiet | 5001 | Ref | 0.014 (0.003, 0.025) | 0.022 (0.010,.033) | 0.0003 |
| MedDiet*Western diet | Ref | −0.020 (−0.037, −0.005) | −0.012 (−0.028,0.003) | 0.13 | |
|
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| Stratified Analysis | |||||
|
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| Low Western Diet group | |||||
|
| |||||
| Basic model | 2508 | Ref | 0.013 (0.002, 0.024) | 0.020 (0.007, 0.033) | 0.002 |
|
| |||||
| Basic + CVD§ | 2489 | Ref | 0.013 (0.002, 0.024) | 0.019 (0.007, 0.032) | 0.003 |
|
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| High Western Diet group | |||||
|
| |||||
| Basic model | 2493 | Ref | −0.006(−0.018, 0.005) | 0.010 (−0.002, 0.022) | 0.09 |
|
| |||||
| Basic + CVD§ | 2470 | Ref | −0.007 (−0.019, 0.005) | 0.010 (−0.002, 0.022) | 0.09 |
Basic model adjusted for age, sex, race, education, physical activity, late life cognitive activity and total calories intake, time and interaction term between time and each model covariate.
β=beta coefficient from the model for the interaction term between MIND diet score and time
Interaction model was basic model additionally controlled for western diet score and MedDiet*western diet
CVD: cardiovascular conditions included diabetes, hypertension, stroke and myocardial infarction.