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. 2022 Dec 20;23:1025. doi: 10.1186/s13063-022-06990-7

Table 2.

Primary and secondary outcomes

Outcomes Sanfu herbal patch (n = ) Placebo (n = ) SHP vs placebo
Difference (95% CI)
p-value
FEV1, L
 1stTS
 2ndTS
 3rdTS
 12 weeks follow-up
 24 weeks follow-up
AQLQ
 2ndTS
 3rdTS
 12 weeks follow-up
 24 weeks follow-up
ACT
 2ndTS
 3rdTS
 12 weeks follow-up
 24 weeks follow-up
IL-5, pg/ml
 2ndTS
 3rdTS
IL-13, pg/ml
 2ndTS
 3rdTS
IL-23, pg/ml
 2ndTS
 3rdTS
IL-25, pg/ml
 2ndTS
 3rdTS
Metallothionein-2, ng/ml
 2ndTS
 3rdTS
Transgelin-2, ng/ml
 2ndTS
 3rdTS
ALFS
 12 weeks follow-up
 24 weeks follow-up

SHP Sanfu herbal patch, FEV1 forced expiratory volume in the first second, AQLQ Asthma Quality of Life Questionnaire, ACT Asthma Control Test, IL-5 interleukin 5, IL-13 interleukin 13, IL-23 interleukin 23, IL-25 interleukin 25, ALFS Asthma Long-term Follow-up Scale, TS treatment session