Table 2.
Variables | LCD score level | Model 1 | Model 2 | Model 3 | |||
---|---|---|---|---|---|---|---|
OR (95%CI) | P | OR (95%CI) | P | OR (95%CI) | P | ||
CERAD word learning subtest # | < 4 | Ref | Ref | Ref | |||
4–8 | 0.58 (0.43–0.78) | 0.001 | 0.59 (0.44–0.80) | 0.003 | 0.56 (0.42–0.75) | 0.003 | |
8–12 | 0.58 (0.44–0.78) | 0.001 | 0.58 (0.43–0.79) | 0.002 | 0.60 (0.42–0.86) | 0.019 | |
12–17 | 0.49 (0.33–0.71) | < 0.001 | 0.53 (0.37–0.77) | 0.003 | 0.56 (0.38–0.82) | 0.014 | |
> 17 | 0.68 (0.50–0.91) | 0.016 | 0.74 (0.55–1.01) | 0.071 | 0.78 (0.55–1.10) | 0.185 | |
AFT* | < 4 | Ref | Ref | Ref | |||
4–8 | 0.72 (0.53–0.97) | 0.041 | 0.76 (0.55–1.04) | 0.098 | 0.72 (0.52–1.00) | 0.186 | |
8–12 | 0.65 (0.47–0.90) | 0.014 | 0.68 (0.48–0.95) | 0.034 | 0.70 (0.48–1.03) | 0.213 | |
12–17 | 0.61 (0.46–0.81) | 0.002 | 0.70 (0.53–0.93) | 0.023 | 0.73 (0.54–0.98) | 0.170 | |
> 17 | 0.84 (0.57–1.23) | 0.374 | 0.96 (0.65–1.43) | 0.856 | 1.00 (0.65–1.52) | 0.984 | |
DSST& | < 4 | Ref | Ref | Ref | |||
4–8 | 0.72 (0.53–0.97) | 0.041 | 0.76 (0.55–1.04) | 0.098 | 0.72 (0.52–1.00) | 0.186 | |
8–12 | 0.65 (0.47–0.90) | 0.014 | 0.68 (0.48–0.95) | 0.034 | 0.70 (0.48–1.03) | 0.213 | |
12–17 | 0.61 (0.46–0.81) | 0.002 | 0.70 (0.53–0.93) | 0.023 | 0.73 (0.54–0.98) | 0.170 | |
> 17 | 0.84 (0.57–1.23) | 0.374 | 0.96 (0.65–1.43) | 0.856 | 1.00 (0.65–1.52) | 0.984 |
Note: LCD Low-carbohydrate-diet, CERAD Consortium to Establish a Registry for Alzheimer’s Disease, AFT Animal Fluency Test, DSST Digit Symbol Substitution Test, OR Odds ratio, CI Confidence interval
Model 1, did not adjust for any confounders;
Model 2, adjusted for age, gender and race;
Model 3 (for CERAD word learning subtest #), adjusted for age, education level, marital status, household income, history of diabetes, hypertension, congestive heart failure, coronary heart disease, heart disease and stroke, magnesium and the using of psychotropic medication;
Model 3 (for AFT*), adjusted for age, gender, race, education level, marital status, household income, body mass index; history of diabetes, hypertension, congestive heart failure, coronary heart disease, heart disease and stroke, magnesium, calcium and the using of psychotropic medication;
Model 3 (for DSST&), adjusted for age, gender, race, education level, marital status, household income, body mass index; history of diabetes, hypertension, congestive heart failure, coronary heart disease, heart disease and stroke, magnesium and calcium