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. 2022 Dec 20;22:983. doi: 10.1186/s12877-022-03607-1

Table 2.

The association between LCD score and cognitive performance

Variables LCD score level Model 1 Model 2 Model 3
OR (95%CI) P OR (95%CI) P OR (95%CI) P
CERAD word learning subtest #  < 4 Ref Ref Ref
4–8 0.58 (0.43–0.78) 0.001 0.59 (0.44–0.80) 0.003 0.56 (0.42–0.75) 0.003
8–12 0.58 (0.44–0.78) 0.001 0.58 (0.43–0.79) 0.002 0.60 (0.42–0.86) 0.019
12–17 0.49 (0.33–0.71)  < 0.001 0.53 (0.37–0.77) 0.003 0.56 (0.38–0.82) 0.014
 > 17 0.68 (0.50–0.91) 0.016 0.74 (0.55–1.01) 0.071 0.78 (0.55–1.10) 0.185
AFT*  < 4 Ref Ref Ref
4–8 0.72 (0.53–0.97) 0.041 0.76 (0.55–1.04) 0.098 0.72 (0.52–1.00) 0.186
8–12 0.65 (0.47–0.90) 0.014 0.68 (0.48–0.95) 0.034 0.70 (0.48–1.03) 0.213
12–17 0.61 (0.46–0.81) 0.002 0.70 (0.53–0.93) 0.023 0.73 (0.54–0.98) 0.170
 > 17 0.84 (0.57–1.23) 0.374 0.96 (0.65–1.43) 0.856 1.00 (0.65–1.52) 0.984
DSST&  < 4 Ref Ref Ref
4–8 0.72 (0.53–0.97) 0.041 0.76 (0.55–1.04) 0.098 0.72 (0.52–1.00) 0.186
8–12 0.65 (0.47–0.90) 0.014 0.68 (0.48–0.95) 0.034 0.70 (0.48–1.03) 0.213
12–17 0.61 (0.46–0.81) 0.002 0.70 (0.53–0.93) 0.023 0.73 (0.54–0.98) 0.170
 > 17 0.84 (0.57–1.23) 0.374 0.96 (0.65–1.43) 0.856 1.00 (0.65–1.52) 0.984

Note: LCD Low-carbohydrate-diet, CERAD Consortium to Establish a Registry for Alzheimer’s Disease, AFT Animal Fluency Test, DSST Digit Symbol Substitution Test, OR Odds ratio, CI Confidence interval

Model 1, did not adjust for any confounders;

Model 2, adjusted for age, gender and race;

Model 3 (for CERAD word learning subtest #), adjusted for age, education level, marital status, household income, history of diabetes, hypertension, congestive heart failure, coronary heart disease, heart disease and stroke, magnesium and the using of psychotropic medication;

Model 3 (for AFT*), adjusted for age, gender, race, education level, marital status, household income, body mass index; history of diabetes, hypertension, congestive heart failure, coronary heart disease, heart disease and stroke, magnesium, calcium and the using of psychotropic medication;

Model 3 (for DSST&), adjusted for age, gender, race, education level, marital status, household income, body mass index; history of diabetes, hypertension, congestive heart failure, coronary heart disease, heart disease and stroke, magnesium and calcium