TABLE 2.

Monocyte cytokine response to bacterial components^a

Final concn of component	Concn (pg/ml) of:
	IL-12 p70	IL-10	TNF-α
E. coli LPS
10 μg/ml	270 ± 240	630 ± 180	20,000 ± 10,000
1 μgml	310 ± 210	660 ± 240	17,000 ± 9,500
100 ngml	410 ± 260	600 ± 210	15,000 ± 8,300
10 ng/ml	370 ± 220	600 ± 230	11,000 ± 5,700
S. aureus peptidoglycan
10 μg/ml	<30	<50	9,200 ± 890
1 μgml	<30	<50	3,000 ± 100
100 ngml	<30	<50	<50
10 ng/ml	<30	<50	<50
S. aureus lipoteichoic acid
10 μg/ml	<30	<50	1,000 ± 70
1 μgml	<30	<50	<50
100 ngml	<30	<50	<50
10 ng/ml	<30	<50	<50
E. faecalis lipoteichoic acid
10 μg/ml	<30	<50	2,500 ± 570
1 μgml	<30	<50	<50
100 ngml	<30	<50	<50
10 ng/ml	<30	<50	<50

^aMonocytes from three blood donors were purified by adherence and stimulated with purified bacterial components in various concentrations. The concentrations of cytokines in supernatants by 24 h were measured by ELISA. The results represent the mean ± standard error for three blood donors.