Table 8.
Frequencies of abnormal laboratory findings in cows with LDA, RDA and AV
| Variable | Finding | LDA | RDA | AV | Total | Chi2 | Additional tests | P |
|---|---|---|---|---|---|---|---|---|
| Haematocrit (n = 1979) |
≤ 35% > 35% |
740 (55%) 598a (45%)1 |
133 (39%) 205 (61%) b |
111 (37%) 192 (63%) b |
984 (50%) 995 (50%) |
52** | Boph | < 0.05 |
|
Leukocytes (n = 1973) |
≤ 10,000/µL > 10,000/µL |
1041 (78%) 293 (22%)a |
244 (72%) 94 (28%)a |
181 (60%) 120 (40%)b |
1466 (74%) 507 (26%) |
42** | Boph | < 0.05 |
|
Total protein (n = 1968) |
≤ 80 g/L > 80 g/L |
942 (71%) 387 (29%)a |
251 (74%) 86 (26%)a |
201 (67%) 101 (33%)a |
1394 (71%) 574 (29%) |
4.9 ns | – | – |
|
Fibrinogen (n = 1965) |
≤ 7 g/L > 7 g/L |
1018 (77%) 308 (23%)a |
257 (76%) 80 (24%)a |
222 (73%) 80 (27%)a |
1497 (76%) 468 (24%) |
1.4 ns | – | – |
|
Urea (n = 1974) |
≤ 6.5 mmol/L > 6.5 mmol/L |
1055 (79%) 280 (21%)a |
193 (57%) 143 (43%)b |
118 (39%) 185 (61%)c |
1366 (69%) 608 (31%) |
212** | Boph | < 0.05 |
| Calcium (n = 1608) |
< 2.20 mmol/L ≥ 2.20 mmol/L |
873 (79%)ab 238 (21%) |
221 (83%)b 44 (17%) |
167 (72%)a 65 (28%) |
1261 (78%) 347 (22%) |
10** | Boph | < 0.05 |
| Inorg. phosph. (n = 1610) |
< 1.30 mmol/L ≥ 1.30 mmol/L |
608 (55%)a 504 (45%) |
114 (43%)b 152 (57%) |
73 (32%)c 158 (68%) |
795 (49%) 814 (51%) |
47** | Boph | < 0.05 |
|
Potassium (n = 1972) |
< 4.0 mmol/L ≥ 4.0 mmol/L |
1097 (82%) 237 (18%) |
282 (84%) 53 (16%) |
261 (86%) 42 (14%) |
1640 (83%) 332 (17%) |
3 ns | – | – |
|
Chloride (n = 1970) |
< 95 mmol/L ≥ 95 mmol/L |
575 (43%)a 757 (57%) |
129 (38%)a 207 (62%) |
173 (57%)b 129 (43%) |
877 (45%) 1093 (55%) |
26** | Boph | < 0.05 |
|
Bilirubin (n = 1962) |
≤ 6.5 µmol/L > 6.5 µmol/L |
141 (11%) 1188 (89%)a |
62 (19%) 270 (81%)b |
70 (23%) 231 (77%)b |
273 (14%) 1689 (86%) |
40** | Boph | < 0.05 |
|
AST (n = 1975) |
≤ 103 U/L > 103 U/L |
289 (22%) 1047 (78%)a |
52 (15%) 284 (85%)b |
37 (12%) 266 (88%)b |
378 (19%) 1597 (81%) |
18** | Boph | < 0.05 |
|
γ-GT (n = 1975) |
≤ 30 U/L > 30 U/L |
645 (48%) 691 (52%)a |
70 (21%) 266 (79%)b |
48 (16%) 255 (84%)b |
763 (39%) 1212 (61%) |
164** | Boph | < 0.05 |
|
γ-GT (n = 1975) |
≤ 30 U/L > 30 U/L |
645 (48%) 691 (52%)a |
70 (21%) 266 (79%)b |
48 (16%) 255 (84%)b |
763 (39%) 1212 (61%) |
164** | Boph | < 0.05 |
|
GLDH (n = 1440) |
≤ 25 U/L > 25 U/L |
198 (20%) 769 (80%)a |
21 (8%) 228 (92%)b |
11 (5%) 213 (95%)b |
230 (16%) 1210 (84%) |
46** | Boph | < 0.05 |
|
SDH (n = 1422) |
≤ 7.6 U/L > 7.6 U/L |
20 (2%) 938 (98%) |
7 (3%) 240 (97%) |
7 (3%) 210 (97%) |
34 (2%) 1388 (98%) |
2 ns | – | – |
| Blood pH | < 7.41 | 363 (30%)a | 123 (39%)b | 96 (35%)ab | 582 (32%) | 12** | Boph | < 0.05 |
| (n = 1812) | > 7.45 | 445 (36%) | 94 (30%) | 95 (34%) | 634 (35%) | |||
|
Bicarbonate (n = 1817) |
< 20.0 mmol/L > 30.0 mmol/L |
76 (6%) 496 (41%) ab |
13 (4%) 107 (34%) b |
16 (6%) 123 (44%)a |
105 (6%) 726 (40%) |
10** | Boph | < 0.05 |
| Base excess | < -2.0 mmol/L | 160 (13%) | 39 (13%) | 31 (11%) | 230 (13%) | 10** | Boph | < 0.05 |
| (n = 1810) | > + 2.0 mmol/L | 829 (68%)a | 188 (61%)b | 187(67%)ab | 1204 (67%) | |||
|
L-lactate (n = 209) |
≤ 2.2 mmol/L > 2.2 mmol/L |
89 (77%) 26 (23%)a |
27 (57%) 20 (43%)b |
10 (21%) 37 (79%)c |
126 (60%) 83 (40%) |
45** | Boph | < 0.05 |
| Rumen chloride (n = 1761) |
≤ 25.0 mmol/L > 25.0 mmol/L |
263 (22%) 925 (78%)a |
148 (49%) 154 (51%)b |
164 (61%) 107 (39%)c |
575 (33%) 1186 (67%) |
192** | Boph | < 0.05 |
Within rows, values with different superscripts differ (P < 0.05), Boph Bonferroni post hoc test
ns not significant
Bold values represent the diagnostic sensitivity (a/[a + b]) (true positives identified by the test as positive)
* P < 0.05
**P < 0.01