Supplement 2.

Summary of published reports of cerebellar dysfunction associated with hypoglycemia

Author/year of publication	Age/sex of the patient	Duration of symptoms	Clinical features	Radiological features	Outcome
Berz et al./2008[5]	51 yrs/male	12 h; symptoms developed after self-overdosing of insulin	Limb dysmetria, gait ataxia, dysarthria	MRI showed small vessel ischemic changes	Resolution over 3 months
Shwaninger et al./2002[6]	41 yrs/male	Two years history of recurrent hypoglycemia due to insulinoma	Severe gait ataxia, mild intention tremor	MRI brain showed bilateral posterior limb (internal capsule) and middle cerebellar hyperintensities on T2 images (PET) brain: normal	Persistence of MRI signal change, but some clinical improvement in cerebellar features at 4 months after resection of insulinoma
Kim et al./2000[7]	52 yrs/female	12 h	Ataxia, dysarthria, tremor, giddiness	MRI brain normal; FDG-PET showed decreased glucose uptake: utilization ratio and increased glucose leak in the cerebellum	Complete resolution of cerebellar features over 12 h, following hypoglycemia correction
Agrawal et al./2014[8]	55 yrs/female	8 h	Sudden onset of postural imbalance and incoordination with focal cerebellar signs on the left side	MRI brain normal	Complete resolution of cerebellar features within 20 min of the administration of glucose