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. 2022 Nov 16;7(6):e00691-22. doi: 10.1128/msystems.00691-22

TABLE 2.

Pertinent results of the variations in C14α-demethylase concentration simulation

Metabolites Value in μM (%)
Case 1 Case 2 Case 3 Case 4 Case 5 Case 6
Ergosterol 0 (0%) 0.11 (0.01%) 3.43 (0.27%) 65.41 (5.22%) 79.60 (6.36%) 81.95 (6.55%)
Toxic sterol 589.71 (46.17%) 589.63 (46.17%) 587.18 (46.08%) 222.01 (17.73%) 31.16 (2.49%) 3.64 (0.29%)
Percent ergosterol reduction a 99.68% 98.91% 94.69% 93.74% 93.59%
Is ergosterol dominant? No No No No No
Number of criteria satisfied 0 0 2 2
a

–, not applicable.