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MIC of GEPO and other comparator drugs against M. tuberculosis-resistant isolates
| Antibiotic | MIC (mg/L) |
||||
|---|---|---|---|---|---|
| M. tuberculosis H37Rv ATCC 27294 | INH-resistant ATCC 35822 | RIF-resistant ATCC 35838 | STR-resistant ATCC 35820 | EMB-resistant ATCC 35837 | |
| Gepotidacin | 0.5 | 1 | 0.5 | 0.25 | 0.25 |
| Isoniazid | 0.03 | >64 | 0.03 | 0.03 | 0.03 |
| Rifampicin | 0.06 | 0.03 | 64 | 0.03 | 0.03 |
| Streptomycin | 1 | 1 | 1 | >64 | 1 |
| Ethambutol | 1 | 2 | 2 | 1 | >64 |
| Levofloxacin | 0.25 | 0.5 | 0.12 | 0.25 | 0.5 |
| Amikacin | 0.12 | 0.25 | 0.12 | 0.25 | 0.12 |
