TABLE 5.

Frequency of spontaneous resistance mutants and mutant prevention concentration (MPC) for levofloxacin and gepotidacin against M. fortuitum ATCC 6841

Drugs	MIC (mg/L)	Mutant frequency and fold MIC						Mutant prevention concn (MPC)
		8×	16×	32×	64×	128×	256×
Levofloxacin	0.06	0.8 × 10−5	1.8 × 10−5	3.6 × 10−7	3.5 × 10−7	2.8 × 10−8	0	256× MIC (15.36 mg/L)
Gepotidacin	1	1.1 × 10−7	3.7 × 10−9	0	0	0	0	32× MIC (32 mg/L)