TABLE 6.
MIC of different antibiotics against in vitro spontaneously resistant mutant isolates of M. fortuitum recovered from agar plates containing LVX and CLRa
| Strain/isolate | Source | MIC range (mg/L) for: |
||||
|---|---|---|---|---|---|---|
| GEPO | LVX | CLR | MEM | LZD | ||
| M. fortuitum ATCC 6841 | Wild type | 2 | 0.06 | 1 | 2 | 2 |
| M. fortuitum LVX resistant | Isolated from LVX-containing agar plates inoculated with wild type | 2 | 4 | 0.5 | 4 | 2 |
| M. fortuitum CLR resistant | Isolated from CLR-containing agar plates inoculated with wild type | 2 | 0.12 | >64 | 2 | 2 |
a
GEPO, gepotidacin; LVX, levofloxacin; CLR, clarithromycin; MEM, meropenem; LZD, linezolid.