FIG 2.

Structure of the MTB Ddn (A), Fgd1 (B), FbiA (C), and FbiB (D) complexed with cofactors. (A) Ribbon representation of Ddn with cofactor F₄₂₀ (PDB code 3R5R). The F₄₂₀ (yellow) is shown with a display style of stick. (B) Ribbon representation of Fgd1 complexed with F₄₂₀ (PDB code 3B4Y). The F₄₂₀ (yellow) was displayed in stick. (C) Ribbon representations of the predicted FbiA-FO-GDP complex. The cofactors FO (yellow) and GDP (blue) were displayed in stick. (D) Ribbon representation of FbiB complexed with F₄₂₀ (PDB code 4XOQ). The F₄₂₀ (yellow) was displayed in stick. The identified mutated residues (orange) were represented with a display style of ball and stick. The images were obtained using the Discovery Studio Visualizer v.4.5 software.