TABLE 2.
Comparison of C. trachomatis and C. pneumoniae infection of BSMC
| Treatmenta | No. of inclusionsb | IL-6 secreted (pg/ml)c |
|---|---|---|
| Mock | 150 (40) | |
| C. trachomatis D/IC Cal 8 | 4,096 (1,006)d | 697 (187)e |
| C. pneumoniae TW-183 | 17,241 (3,138) | 6,217 (385) |
BSMC monolayers grown in 11-mm-diameter culture tubes were infected with 106 IFU of C. trachomatis D/IC Cal 8 or C. pneumoniae TW-183. Mock-infected cells were inoculated with a suspension of lysed BGM cells.
Inclusions per coverslip were counted after immunofluorescence staining at 72 h after infection. Values are means (with standard deviations) of three experiments.
IL-6 concentrations in culture supernatants were determined by ELISA at 48 h after infection. Results are means (with standard deviations) of three experiments.
Significantly different from values for C. pneumoniae-infected cells (Welch t test, P ≤ 0.03).
Significantly different from values for C. pneumoniae-infected cells (Welch t test, P ≤ 0.001) and mock-infected cells (Welch t test, P ≤ 0.04).