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. 2022 Dec 22;95(4):429–443.

Table 2. Antimicrobial resistance of C. acnes in acne patients in other countries, in the published literature (1990-2022). Studies including at least 100 patients are shown.

Study period Country Acne patients, n Any antibiotic resistance, n (%) Clin, n (%) Ery, n (%) Azi, n (%) Doxy, n (%) Mino, n (%)
Moon [54], 2011 Korea 100 (30 C. acnes isolates) 11 (36.7) 30% 26.7% NS 2 (6.7) 3 (10)
Mendoza [55], 2005, 2006 Colombia 100 40% 15% 35% NS 9% 1%
Tan [57], 2007 Singapore 262 (174 C. acnes isolates) 14.9% 7.5% 10.3% NS 3.4% 1.7%
Yang [58], 2014 Singapore 149 (45 C. acnes isolates) 15 (33%) 15 (33%) 14 (31%) NS 10 (22%) NS
Luk [56], 2009 Hong Kong 111
(86 C. acnes)
47 (54.7) 53.5% 18 (20.9) NS 14 (16.3) 14 (16.3)
Abdel-Fattah [53], 2011-2012 Egypt 98 patients NR 66% 49% 5% 6% NS
Akhawaja [50], 2020 Jordan 100 55% 59% 73% NS 37% 3%
Aoki [51], 2013-2018 Japan 212 patients (127 C. acnes isolates) NR 2013: 37.5%
2018: 56.5%
2013: 46.9%
2018: 60.9%
NS 2013: 0
2018: 4.3%
2013: 0
2018: 0
Zhu [41], 2015-2017 China, Kunming 375 patients (227 C. acnes isolates) NR 55.5% 57.7% 58.6% 1.3% NS
Fan [42], 2014 China, multicenter 364 patients (312 C. acnes isolates) NR NR 47.8% 47.8% 0.3% 0
Zhang [59], 2016-2017 China, Shanghai 100 (63 C. acnes isolates) NR 18 (28.6%) 31 (49.2%) NS NS 0

NR: not reported, NS: not studied, Clin: clindamycin resistance, Ery: erythromycin resistance, Azi: azithromycin resistance, Doxy: doxycycline resistance, Mino: minocycline resistance.