. 2022 Nov 3;13(6):e02701-22. doi: 10.1128/mbio.02701-22

TABLE 2.

The size and median relative abundance of DD M. tuberculosis in the sputa of the various cohorts used in this study (as determined by the MPN/CFU ratio with or without CF)^c

Cohort	Sample size (n)	MPN^Max/CFU (median [Q1, Q3])	MPN^+CF/CFU (median [Q1, Q3])	MPN^−CF/CFU (median [Q1, Q3])
All	62–63^a	1.73 [1.37, 2.94]	1.55 [1.05, 2.39]	1.43 [0.95, 2.39]
All DS	35	1.85 [1.28, 3.64]	1.61 [0.97, 2.97]	1.51 [0.99, 3.07]
All DR	27–28^a	1.61 [1.38, 2.22]	1.49 [1.18, 2.16]	1.37 [0.91, 1.92]
All-D0	36–37^a	1.60 [1.22, 2.21]	1.43 [0.83, 1.73]	1.28 [0.95, 1.90]
All-W2	26	2.25 [1.52, 5.66]	2.17 [1.43, 5.01]	1.86 [1.27, 3.60]
DS-D0	20	1.52 [1.00, 2.22]	1.40 [0.81, 1.56]	1.23 [0.95, 1.83]
DS-W2	15	3.80 [2.02, 6.22]	3.19 [1.88, 5.89]	2.46 [1.62, 5.47]
DR-D0	16–17^a	1.61 [1.38, 2.21]	1.56 [1.10, 1.89]	1.38 [0.96, 1.90]
DR-W2	11	1.55 [1.34, 2.70]	1.43 [1.27, 2.70]	1.36 [0.79, 1.86]
All paired^b	21–22	0.77 [−0.28, 3.86]	0.83 [0.12, 3.67]	0.83 [−0.42, 1.64]
DS-paired^b	13	1.65 [0.73, 4.40]	1.65 [0.73, 5.36]	1.29 [0.81, 4.40]
DR-paired^b	8–9^a	0.35 [−0.71, 0.05]	0.08 [−0.71, 0.42]	−0.52 [−0.61, −0.06]

Sample size smaller for MPN^+CF due to a contamination event.

Δ[MPN/CFU] values (week 2 versus day 0) are presented.

Abbreviations: DS, drug sensitive; DR, drug resistant; D0, day 0; W2, week 2; MPN, most probable number; MPN^Max, the maximum M. tuberculosis count obtained by MPN with or without CF; CF, culture filtrate.