TABLE 1.

Biochemical data of serum parameters in the four groups of mice^a

Serum parameter	ND-WT	ND-KO	HFD-WT	HFD-KO	ND-WT vs HFD-WT	HFD-WT vs HFD-KO	HFD-KO vs ND-KO vs ND-WT
Triglycerides (mg/dL)	114.0 ± 10.16	91.2 ± 10.56	225.8 ± 18.47	84.0 ± 1.45	***	***	ns
Total cholesterol (mg/dL)	104.4 ± 8.10	87.5 ± 6.30	244.0 ± 20.65	103.8 ± 1.93	***	***	ns
HDL (mg/dL)	75.3 ± 7.21	62.7 ± 4.84	232.0 ± 24.73	83.3 ± 3.42	***	***	ns
LDL (mmol/L)	0.1 ± 0.01	0.2 ± 0.02	1.2 ± 0.07	0.3 ± 0.04	***	***	ns
Glucose (mmol/L)	6.6 ± 0.64	6.9 ± 0.54	10.3 ± 1.12	7.8 ± 0.54	*	ns	ns
Insulin (ng/mL)	0.7 ± 0.18	0.7 ± 0.13	1.7 ± 0.02	0.4 ± 0.07	***	***	ns
Leptin (ng/mL)	13.2 ± 4.26	4.8 ± 0.73	133.3 ± 5.33	56.2 ± 14.98	***	***	ns

^aStudent’s t test, *, P < 0.05; ***, P < 0.001; ns, non significant.