FIG. 1.

The domains of TRAP. (A) Schematic diagram of TRAP: SS, signal sequence; N-10, conserved N-terminal 10 amino acids; A-domain; TSR, thrombospondin type 1 repeat; TM, transmembrane domain; CD, cytoplasmic domain. (B and C) The crystal structure of the CD11b A-domain (22) (B) was used as the template to model the P. yoelii TRAP A-domain (C). Shown in magenta are Mg²⁺ ions coordinated by the MIDAS. The B-cell epitopes of the TRAP A-domain are highlighted as follows: yellow, B1; red, B2; green, B3.