Table 2.
Gene Set Enrichment Analysis (GSEA) Showing the List of Differentially Expressed Gene Sets
| Gene Set Name [# Genes (K)] | Description | # Genes in Overlap (k) | p-value | FDR q-value |
|---|---|---|---|---|
| HALLMARK_TNFA_SIGNALING_VIA_NFKB [200] | Genes regulated by NG-kB in response to TNF [GeneID=7124]. | 37 | 2.61 e−37 | 1.31 e−35 |
| HALLMARK_MYC_TARGETS_V1 [200] | A subgroup of genes regulated by MYC - version 1 (v1). | 24 | 5.56 e−20 | 1.41 e−18 |
| HALLMARK_HYPOXIA [200] | Genes up-regulated in response to low oxygen levels (hypoxia). | 18 | 4.06 e⁻¹³ | 6.77 e−12 |
| HALLMARK_UV_RESPONSE_UP [158] | Genes up-regulated in response to ultraviolet (UV) radiation. | 14 | 2.07 e−10 | 2.59 e−9 |
| HALLMARK_P53_PATHWAY [200] | Genes involved in p53 pathways and networks. | 15 | 4.9 e−10 | 4.9 e−9 |
| HALLMARK_OXIDATIVE_PHOSPHORYLATION [200] | Genes encoding proteins involved in oxidative phosphorylation. | 13 | 3.9 e−8 | 3.25 e−7 |
| HALLMARK_APOPTOSIS [161] | Genes mediating programmed cell death (apoptosis) by activation of caspases. | 11 | 2.63 e−7 | 1.88 e−6 |
| HALLMARK_GLYCOLYSIS [200] | Genes encoding proteins involved in glycolysis and gluconeogenesis. | 12 | 3.09 e−7 | 1.93 e−6 |
| HALLMARK_FATTY_ACID_METABOLISM [158] | Genes encoding proteins involved in metabolism of fatty acids. | 10 | 1.85 e−6 | 1.03 e−5 |
| HALLMARK_ALLOCGRAFT_REJECTION [200] | Genes up-regulates during transplant rejection. | 10 | 1.49 e−5 | 5.74 e⁻5 |