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. 2022 Dec 20;17(12):e0278825. doi: 10.1371/journal.pone.0278825

Table 4. Predictors of self-reported Long COVID symptoms at four weeks follow-up.

Variable Univariable logistic regression Multivariable logistic regression
Odds Ratio (95% CI) p value Adjusted Odds Ratio (95% CI) p value
Age Categories 18 to 45 years Reference - Reference -
46 to 59 years 1.46 (0.91,2.36) 0.12 1.24 (0.68,2.29) 0.48
60 years & above 1.46 (0.79,2.67) 0.22 1.08 (0.48,2.43) 0.86
Sex Male Reference - Reference -
Female 1.33 (0.89,1.97) 0.16 1.29 (0.74,2.25) 0.36
Occupation Unemployed/Student/Homemaker Reference Reference
Professional/Technical/ Administrative/Managerial 1.32 (0.84,2.08) 0.23 1.79 (0.96,3.33)
0.06
Skilled/Unskilled manual 0.65 (0.31,1.34) 0.24 0.82 (0.32,2.09) 0.68
Other 0.98 (0.55,1.74) 0.94 1.15 (0.53,2.48) 0.73
BMI Underweight (<18.5) Reference - Reference -
Normal or lean (18.5–24.9) 2.13 (0.71,6.44) 0.18 1.58 (0.39,6.47) 0.52
Overweight (25.0–29.9) 2.35 (0.76,7.26) 0.14 1.49 (0.35,6.26) 0.58
Obese (≥30.0) 1.05 (0.23,4.82) 0.95 0.56 (0.09,3.44) 0.53
History of substance use 0.75 (0.39,1,44) 0.38 0.95 (0.41,2.16) 0.89
Past history of COVID-19 0.93 (0.33,2.66) 0.90 0.66 (0.20,2.15) 0.49
Pre-existing medical condition 1.69 (1.12,2.55) 0.01 2.00 (1.16,3.44) 0.01
COVID-19 vaccination Not vaccinated Reference - Reference -
Completed 1 dose 1.30 (0.66,2.55) 0.45 1.88 (0.84,4.22) 0.13
Completed 2 doses 2.05 (1.23,3.42) 0.01 2.32 (1.17,4.58) 0.01
Number of COVID-19 symptoms No symptoms Reference - Reference -
1 to 4 symptoms 9.40 (3.99,22.09) <0.001 6.88 (2.74,17.23) <0.001
5 or more symptoms 12.77 (4.89,33.37) <0.001 11.24 (4.00,31.51) <0.001
Severity of COVID-19 disease Mild/Moderate Reference - Reference
Severe/Critical 5.46 (3.22,9.27) <0.001 5.71 (3.00,10.89) <0.001
Care received during COVID-19 disease Home Isolation Reference - - -
Admitted to hospital 3.89 (2.49,6.08) <0.001 - -
Cycle threshold E Gene/N Gene (n = 442) 0.98 (0.94,1.02) 0.38 - -
ORF1a/ORF1b/N/N2 Gene (n = 378) 0.99 (0.95,1.03) 0.53 - -