Table 3. Testing the direct and indirect effects of personality-mortality index and mitochondrial DNA copy number (mtDNAcn) on mortality.
| BLSA (n = 721) | SardiNIA (n = 395) | |
|---|---|---|
| Total effect | Estimate (p-value) | Estimate (p-value) |
| Personality-mortality index | –0.149 (0.001) | –0.022 (0.808) |
| Full effects | ||
| Personality-mortality index | –0.052 (0.260) | –0.019 (0.895) |
| mtDNAcn | –0.020 (0.000) | –0.001 (0.966) |
| Indirect effect | Estimate [nonparametric bootstrap 95% CI] | Estimate [nonparametric bootstrap 95% CI] |
| mtDNAcn | –0.097 [–0.143; –0.03] | –0.004 [–0.169; 0.189] |
BLSA, Baltimore Longitudinal Study of Aging.