Appendix 2—table 5. Summary of parameter estimates for rs4988235(T).
The upper two rows correspond to results obtained assuming the allele age to be the point estimate of the start of selection onset from Itan et al., 2009: 7441 years ago. The middle two rows and the bottom two rows show results assuming the age to be either the lower or the higher ends of the age’s 95% confidence interval from Itan et al., 2009. Columns named ‘long’ and ‘Lat’ indicate the longitude and latitude of the geographic origin of the allele, respectively.
| (95% CI) | (km2/gen) (95% CI) | (km2/gen) (95% CI) | vx (km/gen) (95% CI) | vy (km/gen) (95% CI) | Long | Lat | Allele age (years) | |
|---|---|---|---|---|---|---|---|---|
| Sample age >5000 | 0.0993 (0.0993 to 0.0993) | 20.293 (15.5643 to 25.0226) | 15.642 (9.9963 to 21.2871) | -0.575 (-0.8055 to -0.3446) | 0.435 (0.319–0.5512) | 43 | 51 | 7441 |
| Sample age <5000 | 0.0328 (0.0327 to 0.0329) | 94.901 (94.2585 to 95.5435) | 85.612 (84.6975 to 86.526) | -1.211 (-1.2197 to -1.2019) | -2.5 (-2.5136 to -2.4855) | |||
| Sample age >5000 | 0.0867 (0.0866 to 0.0867) | 24.27 (24.2658 to 24.2734) | 28.328 (28.3234 to 28.3326) | -0.398 (-0.3985 to -0.3984) | -2.055 (-2.0562 to -2.0547) | 35 | 46 | 8683 |
| Sample age <5000 | 0.0321 (0.0319–0.0323) | 97.325 (97.1434–97.5061) | 87.416 (85.6745 to 89.1578) | -2.5 (-2.5 to -2.4997) | -2.389 (-2.3935 to -2.3845) | |||
| Sample age >5000 | 0.0994 (0.0994–0.0994) | 22.92 (15.0004–30.8397) | 17.884 (13.8709 to 21.8967) | 0.327 (0.1726 to 0.4818) | -0.295 (-0.3678 to -0.2229) | 35 | 49 | 6256 |
| Sample age <5000 | 0.0572 (0.057–0.0574) | 95.014 (93.6242–96.4032) | 85.249 (82.9662 to 87.5322) | -2.499 (-2.4992 to -2.4989) | -1.679 (-1.7919 to -1.5658) |