Table 2.
Subgroup analysis on the pooled proportion and patterns of chromosomal disorders among births with congenital anomalies: by country, region, and year of publication in Africa from January, 2000 to October, 2021.
| Variables | Characteristics | Pooled prevalence | I 2 (P value) |
|---|---|---|---|
| By country | Libya | 30.12 (13.17, 47.07) | 96.9% (<0.001) |
| DRC | 19.3 (15.5, 23.03) | — | |
| Cameroon | 18.18 (10.58, 23.7) | — | |
| Egypt | 10.91 (4.04, 17.76) | 99.5% (<0.001) | |
| Morocco | 10.41 (5.8, 14.8) | 80.7% (0.001) | |
|
| |||
| By region | Central Africa | 19.08% (95% CI: 15.74, 22.43) | — |
| North Africa | 15.06% (95% CI: 10.65, 19.47) | 98.9 (<0.001) | |
| Southern Africa | 5.4.0% (95% CI: 2.01, 8.79) | 99% (<0.001) | |
| East Africa | 4.880% (95% CI: 2.56, 7.20) | 91.1% (<0.001) | |
| West Africa | 4.03% (95% CI: 2.88, 5.18) | 38.7% (=0.05) | |
|
| |||
| By year of publication | 2000–2014 | 8.32 (95% CI: 4.23, 12.15) | 99.5% (p < 0.001) |
| 2015–2021 | 8.53% (95% CI: 6.95, 10.12) | 93.8% (p < 0.001) | |
DRC-Democratic Republic of Congo.