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Plug histology. Porcine blood vessels treated with the IMPEDE Embolization plug (Shape Memory Medical, California) ( a ) vs. coils ( b ) at 60 days. Collagen granule (circles) formation at the site of plug deployment helps create a long-term stable clot, offsetting the higher degree of vessel recanalization seen in coils long term. (Images used with permissions from Shape Memory Medical.)
