Table E2.
Hospitalization outcomes for mechanically ventilated patients with COVID-19 based on extracorporeal membrane oxygenation status
| Hospital outcomes of mechanically ventilated patients with COVID-19 |
|||
|---|---|---|---|
| ECMO (n = 126) | No ECMO (n = 117) | P value | |
| Days intubated (median, IQR) | 25.0 (11.0-41.0) | 16.0 (8.0-24.2) | .001 |
| Days intubated pre-ECMO (median, SD) | 4.5 (3.4) | - | - |
| ECMO, h (median, IQR) | 452.0 (235.0-737.8) | - | - |
| LV dysfunction | 14 (11.1%) | 15 (12.8%) | .832 |
| Inotropes | 51 (40.5%) | 20 (17.1%) | <.001 |
| Vasopressors | 122 (96.8%) | 104 (88.9%) | .030 |
| Inhaled pulmonary vasodilators | 67 (53.6%) | 32 (27.4%) | <.001 |
| Neuromuscular blockade | 118 (93.7%) | 53 (45.7%) | <.001 |
| Therapeutic anticoagulation | 124 (98.4%) | 74 (63.2%) | <.001 |
| Steroids | 95 (75.4%) | 60 (51.3%) | <.001 |
| Investigational COVID therapy | 73 (57.9%) | 79 (67.5%) | .159 |
| Blood transfusion | 103 (81.7%) | 50 (42.7%) | <.001 |
| Bleeding complication | 79 (62.7%) | 24 (20.5%) | <.001 |
| Clotting complication | 72 (57.1%) | 35 (29.9%) | <.001 |
| Acute kidney injury | 99 (79.2%) | 81 (69.2%) | .104 |
| Stroke | 7 (5.6%) | 15 (12.8%) | .080 |
| Delirium | 80 (63.5%) | 72 (61.5%) | .856 |
| Length of stay, d (median, IQR) | 39.0 (27.8-56.2) | 29.0 (20.0-40.0) | <.001 |
| Alive at discharge | 69 (54.8%) | 79 (67.5%) | .057 |
ECMO, Extracorporeal membrane oxygenation; IQR, interquartile range; SD, standard deviation; LV, left ventricular.