Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Dec 21;48:101730. doi: 10.1016/j.nantod.2022.101730

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 The Author(s)

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

PMC Copyright notice

Fig. 4 — Humoral immune response induced by KEN445-LNP vaccines after NFI and NI administrations in rats. (a, b) Binding antibodies against S RBD at 7 days (a) and at 14 days (b) after the 2^nd vaccination were measured using ELISA method. (c, d) psVNT₅₀ serum titers against Omicron-BA.1 at 7 days (c) and 14 days (d) after the 2^nd vaccination were determined by a pseudovirus neutralization assay. (e, f) RBD-specific binding antibody at 7 days (e) and 14 days (f) after the 2^nd vaccination with a strategy of 2 injections totaling a 10 μg dose (5 μg + 5 μg) during one vaccination. (a - f) Statistical analyses were performed using GraphPad Prism 8.3.0 software (n = 8; ns means: not significant).