Figure 2.

Altered capillary hemodynamics in 13-month-old sickle cell mice compared to age-matched controls. (A) average maximum capillary RBC velocity in millimeters per second. (B) average frequency of capillary blood flow reversal per minute (C) average velocity of capillary blood flow reversal in millimeters per second (AA: n = 5, average of ~194 vessel segments; SS: n = 7, average of ~390 vessel segments). Error bars are standard error of means (SEM). *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001. Mean comparisons done using Welch's corrected t-test. Results here are only from the mice in the baseline group.