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. 2022 Dec 7;12:939819. doi: 10.3389/fonc.2022.939819

Table 2.

Patients, disease, and transplant characteristics.

Total cohort 96 patients
Sex M/F 57 (70%)/39 (30%)
Age at transplant 56 years (17–73)
Cytogenetic risk (28)
 Favorable
 Intermediate
 Adverse

4 (4%)
79 (82%)
13 (14%)
ELN risk (7)
 Favorable
 Intermediate
 Adverse

15 (16%)
43 (45%)
38 (39%)
Line of treatment before HSCT n.
 None
 1
 2
 3

4 (4%)
69 (72%)
19 (20%)
4 (4%)
Median time to transplant 183.5 days (30 to 645)
HCT-CI
 0
 1
 2
 3
 4
 ≥5

9 (9%)
11 (11%)
17 (18%)
18 (19%)
23 (24%)
18 (19%)
Year of transplant
 2016–2018
 2019–2021

29 (30%)
67 (70%)
Disease status at transplant
 Never treated
 CR1
 CR2
 PR
 Relapse/refractory

6 (6%)
54 (56%)
12 (13%)
6 (6%)
18 (19%)
Conditioning
 ABL
 RIC/NMA

42 (44%)
54 (56%)
Donor
 HLA Id Sibling
 Haploidentical
 Mismatched unrelated
 Matched unrelated

21 (22%)
32 (33%)
15 (16%)
28 (29%)
Stem cell source
 PB
 CB
 BM

67 (70%)
4 (4%)
25 (26%)
GvHD prophylaxis
 CSA+Cy
 CSA+MFA+Cy
 CSA+MFA
 CSA+MTX

4 (4%)
70 (73%)
2 (2%)
20 (21%)
ATG 18 (19%)

M, male; F, female; HCT-CI, hematopoietic cell transplant comorbidity index; CR, complete remission; PR, partial response; ABL, myeloablative; RIC, reduced intensity conditioning; NMA, non-myeloablative conditioning; PB, peripheral blood; CB, cord blood; BM, bone marrow; CSA, cyclosporine A; MFA, micofenolic acid; MTX, methotrexate; CY, cyclophosphamide post-transplant; ATG, anti-thymocyte globulins.