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. 2022 Dec 7;12:939819. doi: 10.3389/fonc.2022.939819

Table 4.

Cox regression for overall survival.

Univariate Multivariate
Variable HR 95% CI p HR 95% CI p
Patients age continuous 1.03 0.99–1.06 0.05 0.99 0.96–1.03 0.8
Lines of previous therapy continuous 1.64 0.99–2.71 0.05 1.19 0.65–2.20 0.6
HCT-comorbidity index continuous 1.26 1.06–1.51 0.009 1.13 0.94–1.36 0.2
Cytogenetic risk adverse vs. others 3.04 1.42–6.53 0.004 1.46 0.61–3.50 0.4
Complete remission at SCT yes vs. no 0.47 0.25–0.89 0.02 0.58 0.27–1.23 0.1
Conditioning reduced intensity vs. myeloablative 2.25 1.13–4.48 0.02 1.67 0.70–4.00 0.2
Acute GvHD 2–4 yes vs. no 3.31 1.66–6.59 0.0007 2.29 1.00–5.31 0.05
Relapse yes vs. no 6.21 3.19–12.11 <0.0001 4.33 2.07–9.06 0.0001
TP53 mutated vs. not mutated 3.34 1.28–8.70 0.01 1.16 0.41–3.32 0.8