TABLE 3.

Meta-analysis results of adverse reactions.

Adverse reaction	Comparision	Number of studies	Effect estimate	Heterogeneity	Test for overall effect
Positive fecal occult blood	PTS plus ASA vs. ASA	3	1.04 [0.25, 4.23]	p = 0.35; I2 = 10%	Z = 0.05; p = 0.96
Upper gastrointestinal bleeding	PTS plus ASA vs. ASA	1	0.67 [0.10, 4.24]	Not applicable	Z = 0.43; p = 0.67
Subcutaneous hemorrhage	PTS plus ASA vs. ASA	2	0.33 [0.01, 8.55]	Not applicable	Z = 0.66; p = 0.51
Bulbar conjunctival hemorrhage	PTS plus ASA vs. ASA	1	0.33 [0.01, 8.45]	Not applicable	Z = 0.67; p = 0.51
Hematuria	PTS plus ASA vs. ASA	1	0.50 [0.04, 5.76]	Not applicable	Z = 0.56; p = 0.58
Gastrointestinal side effects	PNS plus ASA vs. ASA	1	0.65 [0.10, 4.12]	Not applicable	Z = 0.46; p = 0.65
	PTS plus ASA vs. ASA	3	1.35 [0.49, 3.73]	p = 0.57; I2 = 0%	Z = 0.58; p = 0.56
Urticaria	PNS plus ASA vs. ASA	1	2.02 [0.18, 22.65]	Not applicable	Z = 0.57; p = 0.57
	PTS plus ASA vs. ASA	1	2.11 [0.18, 24.37]	Not applicable	Z = 0.60; p = 0.55

Abbreviations: PTS, panaxatriol saponin; ASA, aspirin; PNS, panax notoginseng saponin.