Table 1.
Gene ontology breakdown of significant phosphorylation changes by cellular component
| Aged/young (145) | Aged/aged ELAM (90) | Both (38) | |
|---|---|---|---|
| 1 | Intracellular (132) | Cell (84) | Intracellular (36) |
| 2 | Cell (132) | Cell part (84) | Cell (26) |
| 3 | Intracellular part (132) | Intracellular (83) | Organelle (36) |
| 4 | Cell part (132) | Intracellular part (83) | Intracellular part (36) |
| 5 | Organelle (127) | Organelle (81) | Cell part (36) |
| 6 | Cytoplasm (120) | Cytoplasm (78) | Cell part (36) |
| 7 | Intracellular organelle (119) | Intracellular organelle (78) | Cytoplasm (33) |
| 8 | Cytoplasmic part (109) | Organelle part (70) | Intracellular organelle (33) |
| 9 | Organelle part (107) | Cytoplasmic part (68) | Organelle part (31) |
| 10 | Non-membrane-bounded organelle (99) | Intracellular organelle part (62) | Cytoplasmic part (31) |
| Nucleus | 64 | 40 | 18 |
| Mitochondrion | 13 | 9 | 5 |
| Endoplasmic reticulum | 9 | 7 | 3 |
| Golgi | 1 | 1 | 0 |
| Vesicle | 53 | 29 | 15 |
| Cytoskeleton | 83 | 47 | 20 |
| Plasma membrane | 36 | 29 | 10 |
| Cytosol | 33 | 24 | 12 |
| Myofibril | 78 | 42 | 23 |
| Extracellular region | 52 | 28 | 15 |
Ten most frequent cellular components and selection of major skeletal muscle organelles are shown. Number of residues significantly altered are shown in parentheses and for selected processes. One-way ANOVA p < 0.05