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. 2022 Nov 2;44(6):2913–2924. doi: 10.1007/s11357-022-00679-0

Table 2.

Gene ontology breakdown of significant phosphorylation changes by biological process

Aged/young (145) Aged/aged ELAM (90) Both (38)
1 Cellular process (124) Cellular process (74) Cellular process (34)
2 Single-organism process (113) Single-organism process (73) Single-organism process (32)
3 Single-organism cellular process (110) Single-organism cellular process (65) Single-organism cellular process (30)
4 Biological regulation (102) Biological regulation (62) Biological regulation (28)
5 Regulation of biological process (100) Multicellular organismal process (60) Regulation of biological process (27)
6 Regulation of cellular process (98) Regulation of biological process (60) Regulation of cellular process (27)
7 Multicellular organismal process (92) Single-multicellular organism process (56) Multicellular organism process (26)
8 Response to stimulus (88) Regulation of cellular process (55) Single-multicellular organism process (25)
9 Cellular component organization (84) Developmental process (53) Response to stimulus (24)
10 Cellular component organization or biogenesis (83) Anatomical structure development (53) Developmental process (22)
Muscle contraction 63 29 19
Metabolic process 75 45 20
Response to oxidative stress 7 2 1
Oxidative phosphorylation 5 2 2

Ten most frequent biological processes and a selection of processes hypothesized to be affected by ELAM are shown. Number of residues significantly altered are shown in parentheses and for selected processes. One-way ANOVA p < 0.05