Table 4.
Odds ratios (and 95% CIs) for nonalcoholic fatty liver disease by quintile of saturated fatty acids after exclusion of patients with a history of alcohol use.
| Variables | Quintile 2 | Quintile 3 | Quintile 4 | Quintile 5 | p for trend | Per 1 SD |
|---|---|---|---|---|---|---|
| LSFAs | ||||||
| 14:0 (myristic acid) | ||||||
| Univariable Model | 1.869 (0.960,3.638) | 2.861 (1.450,5.647) | 5.677 (2.733,11.792) | 8.516 (3.774,19.217) | 0.000 | 3.816 (2.139,6.806) |
| Multivariable Model 1 | 1.811 (0.918,3.573) | 2.588 (1.293,5.181) | 5.387 (2.557,11.353) | 8.481 (3.702,19.428) | 0.000 | 3.762 (2.112,6.701) |
| Multivariable Model 2 | 1.603 (0.776,3.312) | 2.236 (1.070,4.673) | 4.560 (2.082,9.987) | 8.687 (3.634,20.768) | 0.000 | 3.597 (2.030,6.375) |
| 16:0 (palmitic acid) | ||||||
| Univariable Model | 0.901 (0.468,1.735) | 1.335 (0.692,2.577) | 2.836 (1.365,5.891) | 3.845 (1.780,8.307) | 0.000 | 1.489 (1.022,2.170) |
| Multivariable Model 1 | 0.901 (0.459,1.769) | 1.340 (0.678,2.651) | 2.482 (1.171,5.264) | 3.876 (1.746,8.602) | 0.001 | 1.419 (0.968,2.080) |
| Multivariable Model 2 | 0.866 (0.424,1.768) | 1.208 (0.586,2.489) | 2.156 (0.968,4.799) | 3.679 (1.595,8.484) | 0.004 | 1.364 (0.960,1.940) |
| 18:0 (stearic acid) | ||||||
| Univariable Model | 0.624 (0.322,1.208) | 1.167 (0.580,2.348) | 1.445 (0.713,2.930) | 1.471 (0.726,2.979) | 0.082 | 0.945 (0.769,1.161) |
| Multivariable Model 1 | 0.602 (0.306,1.183) | 0.949 (0.459,1.961) | 1.314 (0.638,2.707) | 1.322 (0.633,2.760) | 0.161 | 0.923 (0.743,1.146) |
| Multivariable Model 2 | 0.564 (0.276,1.154) | 0.999 (0.456,2.190) | 1.282 (0.594,2.766) | 1.617 (0.738,3.540) | 0.078 | 0.995 (0.805,1.230) |
| VLSFAs | ||||||
| 20:0 (arachidic acid) | ||||||
| Univariable Model | 1.103 (0.563,2.160) | 1.196 (0.609,2.350) | 1.619 (0.790,3.317) | 0.939 (0.481,1.830) | 0.633 | 0.987 (0.797,1.221) |
| Multivariable Model 1 | 1.259 (0.629,2.518) | 1.197 (0.601,2.384) | 1.758 (0.839,3.681) | 0.914 (0.460,1.815) | 0.492 | 0.967 (0.780,1.199) |
| Multivariable Model 2 | 1.482 (0.704,3.118) | 1.530 (0.728,3.215) | 2.162 (0.982,4.758) | 1.308 (0.625,2.735) | 0.423 | 1.067 (0.847,1.344) |
| 22:0 (behenic acid) | ||||||
| Univariable Model | 1.808 (0.895,3.652) | 1.184 (0.609,2.300) | 1.312 (0.669,2.573) | 1.372 (0.696,2.705) | 0.572 | 1.532 (0.710,3.307) |
| Multivariable Model 1 | 1.568 (0.763,3.221) | 1.026 (0.518,2.032) | 1.166 (0.586,2.322) | 1.233 (0.613,2.478) | 0.762 | 1.590 (0.723,3.495) |
| Multivariable Model 2 | 1.871 (0.866,4.042) | 1.156 (0.558,2.394) | 1.300 (0.623,2.713) | 1.642 (0.779,3.462) | 0.495 | 2.133 (0.890,5.113) |
| 24:0 (lignoceric acid) | ||||||
| Univariable Model | 0.729 (0.371,1.432) | 1.074 (0.521,2.211) | 0.686 (0.348,1.353) | 1.020 (0.499,2.086) | 0.583 | 1.108 (0.828,1.482) |
| Multivariable Model 1 | 0.711 (0.356,1.421) | 1.066 (0.510,2.229) | 0.646 (0.322,1.298) | 1.113 (0.533,2.326) | 0.430 | 1.125 (0.810,1.563) |
| Multivariable Model 2 | 0.805 (0.383,1.694) | 1.113 (0.508,2.438) | 0.632 (0.298,1.342) | 1.426 (0.643,3.164) | 0.282 | 1.263 (0.865,1.845) |
LSFAs, long-chain saturated fatty acids; VLSFAs, Very-long-chain saturated fatty acids; Ref, reference.
Quintile1 is used as reference.
Multivariable Model 1 was adjusted for age, gender, duration of diabetes.
Multivariable Model 2 was adjusted for age, gender, duration of diabetes, body mass index, waist circumference.