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. 2022 Dec 7;13:1095427. doi: 10.3389/fimmu.2022.1095427

Figure 8.

Figure 8

HIF-1α and BNIP3L pathway may induce SAE by promoting apoptosis of hippocampus neurons. Sepsis induce apoptosis of hippocampus neurons, after administration of HIF-1α inhibitor, apoptosis of hippocampus neurons was reduced.