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. 2022 Dec 7;14:1035746. doi: 10.3389/fnagi.2022.1035746

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Copyright © 2022 Yuan, Liang, Xue, Qi, Chen, Song, Wu, Zhang, Xiao and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Anterior cingulate cortex subregions functional connectivity in patients with amnestic mild cognitive impairment (aMCI) compared to subjective cognitive decline (SCD). (A) Functional connectivity (FC) of left caudal anterior cingulate cortex subregion (L-A1) between SCD and aMCl patients. A bar chart indicating the quantitative comparison of FC between these regions. (B) FC of right dorsal anterior cingulate cortex subregion (R-A2) between SCD and aMCI patients. A bar chart indicating the quantitative comparison of FC between these regions. (C) FC of right subgenual anterior cingulate cortex subregion (R-A3) between SCD and aMCI patients. A bar chart indicating the quantitative comparison of FC between these regions. Only the subnetworks that show between-group differences are shown here. All results are displayed after adjusting for age, sex, and education. A threshold of p < 0.05 was applied, with a TFCE-FWE correction with cluster size > 200 mm³. FC, functional connectivity; SCD, subjective cognitive decline; aMCI, amnestic mild cognitive impairment; PCC.L, left posterior cingulate; MFG.R, right middle frontal gyrus; ACC.L, left anterior cingulate. ***p < 0.05.