TABLE 2.
Demographics and clinical measures of healthy control (HC) and patients with subjective cognitive decline (SCD), and amnestic mild cognitive impairment (aMCI).
| Characteristics | HC | SCD | aMCI | F-values (χ2) | p-values |
|
|
|||||
| n = 78 | n = 66 | n = 71 | |||
| Age (years) | 63.56 (6.914) | 65.55 (7.519) | 65.13 (7.625) | 1.488 | 0.228 |
| Gender (male/female) | 29/49 | 15/51 | 25/46 | 3.899 | 0.142 |
| Education level (years) | 12.41 (2.637) | 11.78 (2.715) | 11.05 (2.938)b | 4.51 | 0.012* |
| Composite Z scores of each cognitive domain | |||||
| Episodic memory | 0.25 (0.90) | 0.39 (0.86) | −0.63 (0.93)bc | 25.943 | 0.000* |
| Information processing speed | 0.28 (1.02) | 0.17 (1.01) | −0.46 (0.78)bc | 12.624 | 0.000* |
| Executive function | 0.11 (0.15) | −0.19 (1.77) | 0.06 (0.17) | 1.782 | 0.171 |
| Visuospatial function | −0.18 (1.58) | 0.14 (0.38) | 0.08 (0.27) | 2.193 | 0.114 |
Data are presented as mean (standard deviation, SD). HC, healthy controls; SCD, subjective cognitive decline; aMCI, amnestic mild cognitive impairment. *Significant differences were found among HC, SCD, and aMCI subjects. Most p-values were obtained using ANOVA, except for gender (chi-square test). Comparisons of each paired group were conducted to further reveal the source of ANOVA difference (a: SCD vs. HC; b: aMCI vs. HC; c: aMCI vs. SCD). Bonferroni correction was applied for multiple group comparisons. This study utilized the composite Z scores to determine the level of each cognitive domain. *p < 0.05.