TABLE 3.
Comparisons of functional connectivity of anterior cingulate cortex subregions.
| Brain regions | L/R | MNI | F/T-values | Cluster size (mm3) | ||
|
|
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| X | Y | Z | ||||
| L-caudal ACC functional connectivity | ||||||
| HC vs. SCD | ||||||
| Precuneus | L | −6 | −42 | 39 | 5.1936 | 811 |
| SCD vs. aMCI | ||||||
| Posterior cingulate | L | −3 | −39 | 39 | −4.263 | 369 |
| R-caudal ACC functional connectivity | ||||||
| HC vs. SCD | ||||||
| Precuneus | L | −9 | −66 | 36 | 4.3885 | 147 |
| L-dorsal ACC functional connectivity | ||||||
| HC vs. aMCI | ||||||
| Inferior frontal gyrus | L | −36 | 33 | 15 | 3.4944 | 136 |
| R-dorsal ACC functional connectivity | ||||||
| HC vs. SCD | ||||||
| Middle occipital gyrus | L | −15 | −66 | 36 | 4.5533 | 407 |
| Inferior parietal lobule | L | −51 | −42 | 48 | 3.7425 | 150 |
| SCD vs. aMCI | ||||||
| Middle frontal gyrus R | −15 | 48 | 6 | 3.853 | 242 | |
| L-subgenual ACC functional connectivity | ||||||
| HC vs. SCD | ||||||
| Superior frontal gyrus | L | −9 | 57 | −24 | 4.2268 | 282 |
| R-subgenual ACC functional connectivity | ||||||
| HC vs. SCD | ||||||
| Middle temporal gyrus | L | −45 | −75 | 30 | 4.1189 | 167 |
| HC vs. aMCI | ||||||
| Medial frontal gyrus | L | −6 | 33 | −3 | 27.317 | 355 |
| SCD vs. aMCI | ||||||
| Anterior cingulate | L | −6 | 33 | −3 | 25.197 | 121 |
HC, healthy controls; SCD, subjective cognitive decline; aMCI, amnestic mild cognitive impairment; L, left hemisphere; R, right hemisphere; MNI, Montreal neurological institute. The x, y, z coordinates are the primary peak locations in the MNI space. All results are displayed after adjusting for age, sex, and education at a threshold of p < 0.05, after applying TFCE-FEW correction with cluster size > 200 mm3.