TABLE 2.
Characteristic | Overall | Early death | p | |
---|---|---|---|---|
No | Yes | |||
n | 14,582 | 12,061 | 2,521 | |
Age [mean (SD)] | 61.65 (14.04) | 60.42 (13.83) | 67.51 (13.53) | <0.001 |
Sex (%) | 0.279 | |||
Female | 14,403 (98.8) | 11,907 (98.7) | 2,496 (99.0) | |
Male | 179 (1.2) | 154 (1.3) | 25 (1.0) | |
Race (%) | 0.237 | |||
American Indian/Alaska Native | 92 (0.6) | 79 (0.7) | 13 (0.5) | |
Asian or Pacific Islander | 1,104 (7.6) | 925 (7.7) | 179 (7.1) | |
Black | 2,130 (14.6) | 1741 (14.4) | 389 (15.4) | |
White | 11,201 (76.8) | 9,266 (76.8) | 1,935 (76.8) | |
Unknown | 55 (0.4) | 50 (0.4) | 5 (0.2) | |
Marital status (%) | <0.001 | |||
Married (which includes common law) | 6,370 (43.7) | 5,517 (45.7) | 853 (33.8) | |
Separated, divorced, or widowed | 4,157 (28.5) | 3,243 (26.9) | 914 (36.3) | |
Single (never married) | 3,199 (21.9) | 2,594 (21.5) | 605 (24.0) | |
Others | 856 (5.9) | 707 (5.9) | 149 (5.9) | |
Geographic areas (%) | 0.013 | |||
Metropolitan counties | 12,927 (88.7) | 10,734 (89.0) | 2,193 (87.0) | |
Nonmetropolitan counties | 1,635 (11.2) | 1,312 (10.9) | 323 (12.8) | |
Unknown | 20 (0.1) | 15 (0.1) | 5 (0.2) | |
Laterality (%) | <0.001 | |||
Bilateral, single primary | 90 (0.6) | 65 (0.5) | 25 (1.0) | |
Left—origin of primary | 6,970 (47.8) | 5,828 (48.3) | 1,142 (45.3) | |
Only one side—side unspecified | 48 (0.3) | 39 (0.3) | 9 (0.4) | |
Paired site, but no information concerning laterality | 697 (4.8) | 509 (4.2) | 188 (7.5) | |
Right—origin of primary | 6,777 (46.5) | 5,620 (46.6) | 1,157 (45.9) | |
Brain metastasis (%) | <0.001 | |||
No | 13,031 (89.4) | 10,986 (91.1) | 2,045 (81.1) | |
Unknown | 504 (3.5) | 367 (3.0) | 137 (5.4) | |
Yes | 1,047 (7.2) | 708 (5.9) | 339 (13.4) | |
Liver metastasis (%) | <0.001 | |||
No | 10,843 (74.4) | 9,421 (78.1) | 1,422 (56.4) | |
Unknown | 375 (2.6) | 284 (2.4) | 91 (3.6) | |
Yes | 3,364 (23.1) | 2,356 (19.5) | 1,008 (40.0) | |
Lung metastasis (%) | <0.001 | |||
No | 10,279 (70.5) | 8,872 (73.6) | 1,407 (55.8) | |
Unknown | 506 (3.5) | 376 (3.1) | 130 (5.2) | |
Yes | 3,797 (26.0) | 2,813 (23.3) | 984 (39.0) | |
T stage (%) | <0.001 | |||
T0 | 313 (2.1) | 257 (2.1) | 56 (2.2) | |
T1 | 1,655 (11.3) | 1,454 (12.1) | 201 (8.0) | |
T2 | 3,795 (26.0) | 3,315 (27.5) | 480 (19.0) | |
T3 | 2,004 (13.7) | 1,739 (14.4) | 265 (10.5) | |
T4 | 4,037 (27.7) | 3,254 (27.0) | 783 (31.1) | |
TX | 2,778 (19.1) | 2,042 (16.9) | 736 (29.2) | |
N stage (%) | <0.001 | |||
N0 | 3,468 (23.8) | 2,824 (23.4) | 644 (25.5) | |
N1 | 6,255 (42.9) | 5,295 (43.9) | 960 (38.1) | |
N2 | 1,297 (8.9) | 1,140 (9.5) | 157 (6.2) | |
N3 | 1,730 (11.9) | 1,528 (12.7) | 202 (8.0) | |
NX | 1,832 (12.6) | 1,274 (10.6) | 558 (22.1) | |
Histologic type (%) | <0.001 | |||
Adenomas and adenocarcinomas | 973 (6.7) | 734 (6.1) | 239 (9.5) | |
Ductal and lobular neoplasms | 12,205 (83.7) | 10,489 (87.0) | 1,716 (68.1) | |
Epithelial neoplasms, NOS | 967 (6.6) | 629 (5.2) | 338 (13.4) | |
Squamous cell neoplasms | 14 (0.1) | 9 (0.1) | 5 (0.2) | |
Unspecified neoplasms | 352 (2.4) | 147 (1.2) | 205 (8.1) | |
Others | 71 (0.5) | 53 (0.4) | 18 (0.7) | |
Grade (%) | <0.001 | |||
Grade I | 767 (5.3) | 702 (5.8) | 65 (2.6) | |
Grade II | 3,738 (25.6) | 3,265 (27.1) | 473 (18.8) | |
Grade III | 3,357 (23.0) | 2,844 (23.6) | 513 (20.3) | |
Grade IV | 51 (0.3) | 45 (0.4) | 6 (0.2) | |
Unknown | 6,669 (45.7) | 5,205 (43.2) | 1,464 (58.1) | |
ER status (%) | <0.001 | |||
Borderline/unknown | 1,338 (9.2) | 716 (5.9) | 622 (24.7) | |
Negative | 2,172 (14.9) | 1,647 (13.7) | 525 (20.8) | |
Positive | 11,072 (75.9) | 9,698 (80.4) | 1,374 (54.5) | |
PR status (%) | <0.001 | |||
Borderline/unknown | 1,497 (10.3) | 850 (7.0) | 647 (25.7) | |
Negative | 4,167 (28.6) | 3,328 (27.6) | 839 (33.3) | |
Positive | 8,918 (61.2) | 7,883 (65.4) | 1,035 (41.1) | |
HER2 (%) | <0.001 | |||
Borderline/unknown | 2001 (13.7) | 1,249 (10.4) | 752 (29.8) | |
Negative | 9,784 (67.1) | 8,420 (69.8) | 1,364 (54.1) | |
Positive | 2,797 (19.2) | 2,392 (19.8) | 405 (16.1) | |
Cancer-directed surgery (%) | <0.001 | |||
No | 11,077 (76.0) | 8,722 (72.3) | 2,355 (93.4) | |
Unknown | 244 (1.7) | 225 (1.9) | 19 (0.8) | |
Yes | 3,261 (22.4) | 3,114 (25.8) | 147 (5.8) | |
Radiation (%) | <0.001 | |||
No/unknown | 9,664 (66.3) | 7,681 (63.7) | 1983 (78.7) | |
Yes | 4,918 (33.7) | 4,380 (36.3) | 538 (21.3) | |
Chemotherapy (%) | <0.001 | |||
No/unknown | 6,852 (47.0) | 4,930 (40.9) | 1922 (76.2) | |
Yes | 7,730 (53.0) | 7,131 (59.1) | 599 (23.8) |
SD, standard deviation; T, tumor; N, nodes; NOS, not otherwise specified; ER, estrogen receptor; PR, progesterone receptor; HER2, human epidermal growth factor receptor-2.