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. 2022 May 13;9:68–72. [Article in Italian] doi: 10.33393/grhta.2022.2366

Table S VI.

Analysis of the evolution of the LP of the different generic Erlotinib medicines approved in Spain with respect to the innovative drug.

Drug type & company CIPM approval date Marketing authorization date CIPM LP (€/mg)* Interval since 1st Gx approval by CIPM (years) Price difference vs innovative price Price difference vs 1st Gx approved by CIPM
Innovative (Roche) 25/05/2007 19/09/2005 0.553 NA NA NA
Generic 1 (Teva) 25/04/2019 24/07/2018 0.319 0 -42% NA
Generic 2 (Hetero) 29/02/2020 21/09/2018 0.319 0.8 -42% 0%
Generic 3 (Cipla) 31/05/2020 09/01/2020 0.143 1.1 -74% -55%

* In the case of the innovative drug, the authorized LP at the time of marketing of the first generic drug is indicated.