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. 2022 May 13;9:68–72. [Article in Italian] doi: 10.33393/grhta.2022.2366

TABLE I -.

Maximum drops in the notified LPs experienced by the analysed oncologic drugs, first drops experienced, and time intervals passed until reaching the minimum notified LP since the approval of the LP of the first generic medicine

Drug Patent expiration Date First descent notified LP Maximum descent notified LP Years to minimum LP
Vinorelbine Not available −37% −56% 4.3
Capecitabine 14/12/2013 −39% −68% 1.9
Imatinib 01/12/2016 −40% −97% 4.6
Pemetrexed 10/06/2021 −40% −45% 4.4
Erlotinib 01/03/2020 −42% −74% 1.1
Dasatinib 01/11/2019 −69% −70% 1.3
Gefitinib 01/09/2019 −40% −84% 1.1
Everolimus 17/01/2019 −58% −66% 1.7

LP = list price.