Figure 7.

Identified enriched pathways from urine metabolome urine over gestation and in early pregnancy

(A) Pathway enrichment analysis over gestation using metabolites from urine that were significant (FDR < 0.05, Wilcoxon signed-rank test with Benjamini-Hochberg procedure). Pathways shown above the dotted line were significant (p < 0.05).

(B) Pathway enrichment analysis for early pregnancy using metabolites from urine that were significant (FDR < 0.05, linear mixed-effects model with Benjamini-Hochberg procedure). The color and the size of a circle are proportional to the −log(p) and pathway impact value, respectively, where p denotes a p value.