FIG. 3.

C10 therapy significantly augments peritoneal TNF-α and MCP-1 levels. Mice underwent CLP surgery and received either 500 ng of C10 protein or normal saline alone via i.p. injection immediately after surgery. Peritoneal cytokine concentrations were determined by analyzing peritoneal lavage fluids by cytokine-specific ELISA at 15 min after the CLP surgery. A two-tailed t test was used to assess significance. Three separate experiments were performed (n = 12 mice per group), and the data were pooled. ∗, P < 0.01.