| Atenolol (1) |
His110, Glu149, Asp146 |
Aromatic hydrogen, |
| Phe133 |
Aromatic hydrogen π–π interaction |
| Itopride hydrochloride (2) |
Glu149 |
Hydrogen bonding, aromatic hydrogen interactions |
| Scopolamine hydrobromide trihydrate (3) |
Glu111, Glu149 |
H-bond |
| His110 |
π-cation |
| Phloridzin (4) |
Val 132, Gly81, Cys82, Trp87, Ser56 |
Aliphatic H-bond |
| Glu149 |
Aliphatic H-bond, aromatic hydrogen interactions |
| Cefadroxil monohydrate (5) |
His110 |
H-bond, π–π stacking |
| Glu111, Glu149 |
Aromatic hydrogen interaction |
| Diclofenac sodium (6) |
Glu111, Gly106, His110 |
H-bond, |
| Asp131 |
Aromatic H-bond |
| Epinephrine bitartrate/adrenaline bitartrate (7) |
Glu149, Thr104, Asp79, Gly 86 |
H-bond |
| Trp87 |
Aromatic hydrogen interaction |
| Cloxacillin (8) |
Glu149 |
H-bond |
| Levosulpiride (9) |
His110 |
H-bond and π cation |
| Cinitapride (10) |
Phe133 |
π–π stacking |
| His110, Asp148, Glu149 |
Aromatic hydrogen interaction |
| Boldine (11) |
Asp131, Glu149 |
H-bond linkages and aromatic hydrogen |
| Neohesperidin dihydrochalcone (12) |
Phe133 |
π–π stacking |
| Gly81, Trp87, Lys105, Arg163, Glu149 |
H-bond interaction |
