Table 3.
IOPc and IOPg reduction following LASIK and PRK procedures including paired (post-operative – pre-operative) IOP measurement changes
| Procedural Changes in IOP | LASIK (n = 58) | T-test between groups p= | PRK (n = 62) | T-test between groups p = |
|---|---|---|---|---|
| IOPg (GAT) | ||||
| Mean Pre-Op | 14.8+/−3.0 (20,7) | 14.3+/−2.6 (20,8) | ||
| Mean Post-Op | 11.5+/−2.0 (18,8) | < 0.0001 | 12.4+/−3.1 (19,6) | < 0.0001 |
| IOPc (Mod. GAT) | ||||
| Mean Pre-Op | 16.5+/−2.8 (22,10) | 14.3+/−2.6 (20,8) | ||
| Mean Post Op | 12.8+/−2.1 (18,10) | < 0.0001 | 13.3+/−3.0 (19,6) | < 0.0001 |
| Paired Procedural IOP Change | ||||
| IOPg (Post-Pre) | (−)3.27+/−3.2 (4,-10) | (−)1.92+/−3.6 (7,-10) | ||
| IOPc (Post-Pre) | (−)1.93+/−3.3 (8,-8) | < 0.0001 | (−)1.06+/− 3.6 (7,-8) | < 0.0001 |
IOPc and IOPg Reduction with Ablation Depth and CCT Reduction. Correlations to the measured parameters following LASIK and PRK were not statistically significant (Tables 4 and 5). It should be noted, however, that increased ablation depth and decreased CCT trended toward lower post-operative IOP measured with IOPc and IOPg (Fig. 2). The GAT reduction in IOP following LASIK was nearly significant following LASIK (−)0.24 mmHg/μm (p = 0.07)