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Microfilament polymerization is required for lymphocyte proliferation in response to C. neoformans. PBMC were stimulated with C. neoformans (A) or with ConA (B) in the presence or absence of various concentrations of cytochalasin B. ∗, P < 0.05 compared to cells stimulated in the absence of cytochalasin B. Phagocytosis is expressed as the mean of duplicate determinations. The experiment was repeated twice with similar results.
