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. 2022 Nov 30;96(24):e01082-22. doi: 10.1128/jvi.01082-22

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Copyright © 2022 Yang et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 3 — V2i Fabs adopt a variety of poses to recognize Env-sCD4. Fab heavy chains (HCs) are dark blue, light chains (LCs) are light blue, sCD4 is yellow, gp120 is light gray, gp41 is dark gray, and the ordered portion of gp120 V1V2 is orange. (A) Structures are shown as surface representations. A disordered V3 loop is indicated by dotted lines. (B) Surface depictions of previous CD4i Fab-Env-sCD4 complex structures: E51-BG505-sCD4 (PDB code 6U0L), 17b-BG505-sCD4-8ANC195 (PDB code 6CM3), and 21c-B41-sCD4-8ANC195 (PDB code 6EDU).