Fig. 7. (A) Schematic showing the growth of flower-like CaCO₃ crystals on negative-potential-charged microporous starch (MSS) during the synthesis of Janus MSS@CaCO₃ particles. (B) SEM images of MSS@CaCO₃ Janus particles with different aspect ratios of [MSS]/[CaCO₃]: (a) 1 : 0.1, (b) 1 : 0.5, (c) 1 : 1, and (d) 1 : 2. (C) Whole blood in vitro clotting time. (D) Representative TEG parameters of whole blood treated with particles. Images of hemostasis in liver (E) and femoral artery (F) bleeding models. Histological sections from (G) liver bleeding models and (H) femoral artery bleeding models treated with (a) MSST and (b) Janus MSS@CaCO₃T. Histological sections from in vivo biodegradation models treated with Celox (I) and Janus MSS@CaCO₃T (J). Adapted with permission from ref. ²⁵³. Copyright 2020, Wiley-VCH GmbH.