TABLE 1.
Characteristics | Population of PWH with genotype available during study period (2012 to 2017)b | Population of PWH without a genotype available during study period (2012 to 2017) | Cluster status of population with genotype during 2012 to 2017 (N = 27,115) |
Cluster status of population with genotype during 2012 to 2017 diagnosed 2010 and beyond (n = 12,475) |
||||
---|---|---|---|---|---|---|---|---|
Clustered (n = 4,943) |
Unclustered (n = 22,172) |
Clustered vs. unclustered aORc (95% CId) |
Clustered (n = 4,007) |
Unclustered (n = 8,468) |
Clustered vs. unclustered aOR (95% CI) |
|||
HIV Dxe yr | ||||||||
2016 to 17 | 5,146 (15.2%) | 4,343 (2.6%) | 1,426 (28.8%) | 2,306 (10.4%) | Referent | 1,323 (33.0%) | 2,409 (28.4%) | Referent |
2014 to 15 | 5,374 (15.9%) | 3,848 (2.3%) | 1,846 (37.3%) | 2,720 (12.3%) | 0.85 (0.76 to 0.95) | 1,710 (42.7%) | 2,856 (33.7%) | 0.82 (0.73 to 0.94) |
2012 to 13 | 2,788 (8.3%) | 5,994 (3.6%) | 815 (16.5%) | 1,844 (8.3%) | 0.48 (0.41 to 0.55) | 731 (18.2%) | 1,928 (22.8%) | 0.45 (0.38 to 0.53) |
2010 to 11 | 1,842 (5.5%) | 7,452 (4.5%) | 278 (5.6%) | 1,240 (5.6%) | 0.23 (0.19 to 0.27) | 243 (6.1%) | 1,275 (15.1%) | 0.21 (0.18 to 0.26) |
<2010 | 15,069 (44.6%) | 144,339 (87.0%) | 578 (11.7%) | 14,062 (63.4%) | 0.04 (0.04 to 0.05) | |||
Sampling yr | ||||||||
Median (IQRf) | Not available | Not available | 2015 (2014 to 16) | 2015 (2014 to 16) | 0.88 (0.85 to 0.91) | 2015 (2014 to 16) | 2015 (2014 to 16) | 0.87 (0.83 to 0.91) |
Birth region | ||||||||
North America | 21,869 (64.7%) | 122,510 (73.8%) | 3,781 (81.4%) | 16,437 (77.6%) | Referent | 3,014 (80.5%) | 5,492 (70.1%) | Referent |
Africa | 122 (0.4%) | 578 (0.3%) | 6 (0.1%) | 20 (0.1%) | 0.77 (0.25 to 2.19) | 5 (0.1%) | 8 (0.1%) | 0.68 (0.20 to 2.15) |
Asia Pacific | 168 (0.5%) | 710 (0.4%) | 28 (0.6%) | 74 (0.3%) | 0.82 (0.48 to 1.37) | 26 (0.7%) | 43 (0.5%) | 0.93 (0.53 to 1.60) |
Caribbean | 4,836 (14.3%) | 26,635 (16.0%) | 536 (11.5%) | 3,398 (16.0%) | 0.63 (0.55 to 0.71) | 441 (11.8%) | 1,537 (19.6%) | 0.65 (0.56 to 0.75) |
Europe | 187 (0.6%) | 1,317 (0.8%) | 33 (0.7%) | 119 (0.6%) | 0.56 (0.36 to 0.85) | 29 (0.8%) | 74 (0.9%) | 0.53 (0.33 to 0.83) |
Latin America | 1,701 (5.0%) | 8,640 (5.2%) | 261 (5.6%) | 1,135 (5.4%) | 0.42 (0.35 to 0.50) | 227 (6.1%) | 685 (8.7%) | 0.42 (0.35 to 0.51) |
Age at genotyping (yr) | ||||||||
Mean (SDg) | Not available | Not available | 31.4 (11.5) | 35.1 (12.2) | 0.96 (0.95 to 0.96) | 31.3 (11.3) | 38.7 (13.3) | 0.95 (0.95 to 0.95) |
Sex at birth | ||||||||
Female | 9,096 (26.9%) | 43,270 (26.1%) | 765 (15.5%) | 7,068 (31.9%) | Referent | 542 (13.5%) | 2,205 (26.0%) | Referent |
Male | 21,123 (62.5%) | 122,706 (73.9%) | 4,178 (84.5%) | 15,104 (68.1%) | 1.35 (1.19 to 1.53) | 3,465 (86.5%) | 6,263 (74.0%) | 1.31 (1.13 to 1.53) |
Race/ethnicity | ||||||||
Black | 16,556 (49.0%) | 77,817 (46.9%) | 2,354 (47.6%) | 12,212 (55.1%) | Referent | 1,826 (45.6%) | 4,325 (51.1%) | Referent |
Hispanic/Latino | 6,511 (19.3%) | 31,810 (19.2%) | 1,215 (24.6%) | 4,339 (19.6%) | 1.32 (1.18 to 1.48) | 1,044 (26.1%) | 2,077 (24.5%) | 1.38 (1.21 to 1.56) |
Other | 692 (2.0%) | 3,293 (2.0%) | 110 (2.2%) | 462 (2.1%) | 1.10 (0.83 to 1.44) | 87 (2.2%) | 156 (1.8%) | 1.09 (0.79 to 1.50) |
White | 6,460 (19.1%) | 53,056 (32.0%) | 1,264 (25.6%) | 5,159 (23.3%) | 1.11 (1.01 to 1.23) | 1,050 (26.2%) | 1,910 (22.6%) | 1.26 (1.12 to 1.41) |
District | ||||||||
Central East | 3,694 (10.9%) | 18,139 (10.9%) | 734 (14.8%) | 66 (12.5%) | Referent | 592 (14.8%) | 1,031 (12.2%) | Referent |
Central West | 4,890 (14.5%) | 23,751 (14.3%) | 854 (17.3%) | 2,769 (16.6%) | 0.80 (0.70 to 0.92) | 725 (18.1%) | 1,469 (17.3%) | 0.86 (0.74 to 1.00) |
Northeast | 7,218 (21.4%) | 14,896 (9.0%) | 715 (14.5%) | 2,804 (12.6%) | 1.05 (0.91 to 1.22) | 558 (13.9%) | 1,030 (12.2%) | 1.01 (0.85 to 1.20) |
Northwest | 1,634 (4.8%) | 6,720 (4.0%) | 282 (5.7%) | 1,246 (5.6%) | 0.86 (0.72 to 1.04) | 226 (5.6%) | 470 (5.6%) | 0.87 (0.71 to 1.07) |
Southeast | 14,982 (44.3%) | 93,646 (56.4%) | 2,140 (43.3%) | 10,633 (48.0%) | 0.90 (0.80 to 1.00) | 1,728 (43.1%) | 4,074 (48.1%) | 0.92 (0.81 to 1.05) |
Southwest | 1,369 (4.1%) | 8,824 (5.3%) | 207 (4.2%) | 983 (4.4%) | 0.88 (0.72 to 1.07) | 170 (4.2%) | 378 (4.5%) | 0.91 (0.73 to 1.15) |
Rural/urban | ||||||||
Rural | 4,759 (14.1%) | 6,871 (4.1%) | 118 (2.4%) | 790 (3.6%) | Referent | 93 (2.3%) | 235 (2.8%) | Referent |
Urban | 29,028 (85.9%) | 159,105 (95.9%) | 4,814 (97.6%) | 21,316 (96.4%) | 1.42 (1.12 to 1.81) | 3,906 (97.7%) | 8,217 (97.2%) | 1.24 (0.94 to 1.66) |
Transmissioncategory | ||||||||
HETh | 11,284 (33.4%) | 48,612 (29.3%) | 1,064 (21.5%) | 8,530 (38.5%) | Referent | 768 (19.2%) | 3,168 (37.4%) | Referent |
IDUi | 3,139 (9.3%) | 27,835 (16.8%) | 344 (7.0%) | 2,830 (12.8%) | 1.17 (1.00 to 1.37) | 255 (6.4%) | 546 (6.4%) | 1.41 (1.16 to 1.72) |
MSMj | 13,939 (41.3%) | 70,153 (42.3%) | 3,377 (68.3%) | 9,376 (42.3%) | 1.56 (1.38 to 1.75) | 2,870 (71.6%) | 4,251 (50.2%) | 1.68 (1.46 to 1.92) |
MTCk | 612 (1.8%) | 1,901 (1.1%) | 31 (0.6%) | 525 (2.4%) | 0.26 (0.17 to 0.38) | 12 (0.3%) | 58 (0.7%) | 0.19 (0.09 to 0.35) |
Unknown | 1,245 (3.7%) | 17,475 (10.5%) | 127 (2.6%) | 911 (4.1%) | 0.84 (0.67 to 1.06) | 102 (2.5%) | 445 (5.3%) | 0.90 (0.69 to 1.16) |
Descriptive results are presented as frequency (column percentage) unless otherwise specified. Missing values were retained as unknown for this table, and therefore, not all proportions and inverse proportions add up to 1.
Sequences were available for 31.6% of the total population living with HIV using state prevalence data (flhealthcharts.com [Accessed 5 April 2020]).
aOR, adjusted odds ratio.
CI, confidence interval.
Dx, diagnosis.
IQR, interquartile range.
SD, standard deviation.
HET, heterosexual.
IDU, intravenous drug use.
MSM, men who have sex with men.
MTC, mother-to-child.