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. 2022 Oct 17;10(6):e01372-22. doi: 10.1128/spectrum.01372-22

TABLE 2.

MICs of BDQ and WX-081 against reference strains of 24 SGM species

Strain by type Mycobacterial species (strain) MIC (μg/mL)
BDQa WX-081b
ATCC 25276 Mycobacterium asiaticum <0.0039 <0.0039
ATCC 25291 Mycobacterium avium 0.0078 0.0156
DSM45069 Mycobacterium arosiense 0.0078 0.0156
DSM 44243 Mycobacterium celatum >2 >2
DSM 44622 Mycobacterium chimaera <0.0039 <0.0039
ATCC 15754 Mycobacterium gastri 0.125 0.125
ATCC 27726 Mycobacterium gadium 0.0156 0.0156
ATCC 14470 Mycobacterium gordonae ≤0.0039 ≤0.0039
ATCC 13950 Mycobacterium intracellulare 0.0078 0.0156
DSM44064 Mycobacterium interjectum 0.0078 0.0078
ATCC 12478 Mycobacterium kansasii 0.0078 0.0156
DSM44627 Mycobacterium kubicae ≤0.0078 ≤0.0078
ATCC 927 Mycobacterium marinum ≤0.0039 0.0078
ATCC 19422 Mycobacterium microti 0.0625 0.125
ATCC 19530 Mycobacterium nonchromogenicum 0.25 0.25
DSM 44648 Mycobacterium parascrofulaceum 0.0078 0.0313
ATCC 27024 Mycobacterium rhodesiae >2 >2
ATCC 19981 Mycobacterium scrofulaceum 0.0156 0.0313
ATCC 35799 Mycobacterium szulgai 0.0126 0.0625
ATCC 33027 Mycobacterium sphagni 0.0156 0.0156
ATCC 27962 Mycobacterium shimoidei 0.25 0.5
ATCC 15755 Mycobacterium terrae ≤0.0039 0.0156
ATCC 23292 Mycobacterium triviale 0.125 0.25
ATCC 19250 Mycobacterium xenopi 0.125 0.25
ATCC 27294 Mycobacterium tuberculosis (H37Rv) 0.0625 0.125
a

BDQ, bedaquiline.

b

WX-081, sudapyridine.