TABLE 2.

IgM antibody detection by DPP HIV-Syphilis assay in active syphilis^a

Sample ID	Days since first bleed	RPR		Testing prior to 2-ME treatment				DPP signal reduction after 2-ME treatment
				DPP HIV-Syphilis		DPP HIV-Syphilis IgM		DPP HIV-Syphilis	DPP HIV-Syphilis IgM
		Result	Titer	Resultb	s/coc	Resultb	s/coc
PSS901-06	45	Positive	1:8	Positive	3.7	Positive	1.4	95%	99%
PSS901-07	48	Positive	1:16	Positive	4.7	Positive	2.0	87%	99%
PSS901-08	52	Positive	1:32	Positive	16.0	Positive	2.6	84%	98%
PSS901-09	59	Positive	1:64	Positive	33.9	Positive	3.6	58%	95%
w36981501276400	NA	Positive	1:1	Positive	5.4	Positive	1.4	91%	100%
w36981501452200	NA	Positive	1:16	Positive	30.7	Positive	2.6	68%	97%
w36981502181900	NA	Positive	1:1	Positive	30.9	Positive	1.4	62%	99%
PRB-933-02	21	ND	NA	Positive	1.3	Positive	1.2	87%	98%
DLS0116358	NA	Positive	1:64	Positive	36.6	Negative	0.9	16%	NA
PRB-912-02	9	ND	NA	Positive	5.7	Negative	0.3	8%	NA

^aRPR, rapid plasma reagin; s/co, signal-to-cutoff ratio; ND, not done; NA, not applicable.

^bResults are shown for treponemal antibodies, all samples were HIV antibody negative, except for PRB-933-02 and PRB-912-02.

^cTest interpretation: positive result at signal-to-cutoff ration (s/co) ≥1.0, negative result at s/co <1.0.